Synonyms        GDF-8, MSTN, Growth Differentiation Factor 8, MSTN Muscle Hypertrophy. 

Type         Polyclonal Rabbit Antibody. 

Introduction         GDF8 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. 

Immunogen           r.Human Myostatin 

Ig Subclass           Rabbit IgG

Antigen Amino Acid Sequence         HHHHHHDFGL DCDEHSTESR CCRYPLTVDF EAFGWDWIIA PKRYKANYCS GECEFVFLQK

YPHTHLVHQA NPRGSAGPCC TPTKMSPINM LYFNGKEQII YGKIPAMVVD RCGCS 

Purification Method        Purified IgG prepared by affinity chromatography on protein G. 

Protein formulation            Lyophilized from 1mg/ml solution in 0.2µm sterile filtered solution in phosphate buffered saline. 

Solubility         Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. 

Stability/Storage           Store at 4°C. For long term storage freezes in working aliquots at -20°C.

Repeated freezing and thawing is not recommended. 

Purity         Greater than 98.0% as determined by Analysis by SDS-PAGE. 

Applications           To detect Human Myostatin by WB analysis this IgG can be used in a dilution of 1/500.

To optimal usage we suggest overnight incubation. 

Usage          CHI's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.