Synonyms   Activin Beta-A chain, Erythroid differentiation protein, EDF, FRP, Activin-A, Inhibin-B, Inihibin-Beta A chain. 

Introduction   Inhibins are dimeric peptide hormones produced by female ovarian granulose cells and male Sertoli cells as well as a variety of other tissues. Inhibins have two isoforms, A and B, with the same alpha subunit but different beta subunits. Inhibin A is a dimer of alpha and beta A subunits, inhibin B is a dimer of alpha and beta B subunits.

Inhibins are thought to inhibit the production of follicle-stimulating hormone (FSH) by the pituitary gland. In addition, Inhibins are also thought to play a role in the control of gametogenesis, and embryonic and fetal development. 

Description   Activin-A Human Recombinant also called Inhibin-Beta A chain produced in E.Coli is a single monomeric, non-glycosylated, polypeptide chain containing 116 amino acids fragment (311-426) and having an amino-terminal hexa-histidine tag, having a total molecular weight of 17.47 kDa.The Activin-A is purified by standard chromatographic techniques. 

Source   Escherichia Coli. 

Physical Appearance   Sterile Filtered clear solution. 

Formulation   Activin-A is supplied in 20mM Tris pH-8 and 50% glycerol. 

Stability   Store Inhibin-Beta, Alpha chain at 4°C if entire vial will be used within 2-4 weeks.  Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. 

Purity   Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. 

Usage   CHI's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.