Synonyms    Fibroblast Growth Factor 15, FGF19. 

Introduction     FGF-15 takes part in the suppression of bile acid biosynthesis by down-regulation of CYP7A1 expression. FGF-15 is expressed in the developing brain. 

Description    FGF-15 Protein is 23.78 kDa protein containing 203 amino acid residues including a 10 a.a. N-Terminal His-tag. 

Source     E. coli 

Formulation    FGF-15 was filtered (0.4µm) and lyophilized from 0.5 mg/ml supplied in 20mM TRIS and 20mM NaCl, pH 8.0. 

Solubility     It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it on cell culture. 

Stability    Store lyophilized FGF-15 at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted FGF-15 can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. 

Amino Acid Sequence    MKHHHHHHAS RPLAQQSQSV SDEDPLFLYG WGKITRLQYL YSAGPYVSNC FLRIRSDGSV DCEEDQNERN LLEFRAVALK TIAIKDVSSV RYLCMSADGK IYGLIRYSEE DCTFREEMDC LGYNQYRSMK HHLHIIFIQA KPREQLQDQK PSNFIPVFHR SFFETGDQLR SKMFSLPLES DSMDPFRMVE DVDHLVKSPS FQK.

Applications    Western blotting 

Usage    CHI's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.