Synonyms Neurofilament medium polypeptide, NF-M, Neurofilament triplet M protein, 160 kDa neurofilament protein, Neurofilament 3, NEFM, NEF3, NFM.
Introduction Neurofilaments are type IV intermediate filament heteropolymers that are composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber and may also have a role in intracellular transport to axons and dendrites.
NeuroFilament 160kDa is a medium neurofilament protein, which is commonly used as a biomarker of neuronal damage.
Description Ultra Pure NeuroFilament Protein having a Molecular mass of 160 kDa produced from Bovine Spinal Cord.
Source Bovine Spinal Cord.
Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation The protein was lyophilized from a 1mg/ml solution containing 10mM sodium phosphate, pH-7.5, 2mM DTT, 6M urea and 1mM EDTA.
Solubility It is recommended to reconstitute the lyophilized NEFM in sterile 18MΩ-cm H2O.
Stability Lyophilized NEFM although stable at room temperature for 3 weeks, should be stored desiccated below -18℃. Upon reconstitution NEFM should be stored at 4℃ between 2-7 days and for future use below
-18℃.
Please prevent freeze-thaw cycles.
Purity Greater than 98.0% as determined by(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Applications Protein standard in 1D and 2D SDS gelelectrophoresis
Immunoassays
Immunization.
Usage CHI's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.